Publications

Below are listed publications resulting from ongoing Center research activities.

Platform-specific Fc N-glycan profiles of an antisperm antibody.

Nador E, Xia C, Santangelo, PJ, Whaley KJ, Costello CE, Anderson D.J Antibodies 2024, 13(1), 17; https://doi.org/10.3390/antib13010017

Innovations in monoclonal antibody-based multipurpose prevention technology (MPT) for the prevention of sexually transmitted infections and unintended pregnancy.

Dohadwala S, Geib, MT, Politch JA, Anderson DJ. Front Reprod Health. 2024 Jan 9:5:1337479. doi: 10.3389/frph.2023.1337479. eCollection 2023.

A brief history and future prospects of contraception

Anderson DJ, Johnston DS. Science. 2023 Apr 14;380(6641):154-158. doi: 10.1126/science.adf9341. Epub 2023 Apr 13.

A brief history and advancement of contraceptive multipurpose prevention technology (cMPT).

Dohadwala S, Politch JA, Barmine JH, Anderson DJ. Open Access Journal of Contraception. 2023; 14: 83-94.

ZB-06, a vaginal film containing an engineered human contraceptive antibody (HC4-N), demonstrates safety and efficacy in a phase 1 postcoital test and safety study

Thurman AR, Moench TR, Hoke M, Politch JA, Cabral H, Mausser E, Nador E, Morton J, Hamorsky K, Swope K, Bratcher B, Anderson DJ, Whaley KJ. Am J Obstet Gynecol. 2023 Jun;228(6):716.e1-716.e12. doi: 10.1016/j.ajog.2023.02.024. Epub 2023 Mar 2.

LALAPG variant of the human contraception antibody (HCA) reduces Fc-mediated effector functions while maintaining sperm agglutination activity

Mausser E*, Nador E*, Politch JA, Pauly MR, Marathe JG, Moench TR, Zeitlin L, Whaley KJ, Anderson DJ. PLOS ONE. 2023 Mar 30;18(3):e0282147. doi: 10.1371/journal.pone.0282147

Passive immunization of the human vagina.

Anderson DJ. Hum Vaccin Immunother. 2022 Apr 7; 18(2): e1965423. doi: 10.21645515. PMID: 3447305, PMCID: PMC9103259.

Engineering ultra-potent sperm binding IgG antibodies for the development of an effective non-hormonal female contraceptive.

Shrestha B, Schafer A, Saada J, Yong Z, Jacobs T, Chavez E, Omsted S, Cruz-Teran C, Baldeon Vaca G, Vincent K, Moench T, Lai S., Science Translational Medicine. 2021 Aug 11; 13(606):eabd5219, doi: 10.1126/scitranslmed.abd5219. PMID: 34380769, PMCID: PMC8868023

Production and characterization of a human antisperm monoclonal antibody against CD52g for topical contraception in women.

Baldeon Vaca G, Marathe JG, Politch JA, Mausser E, Pudney J, Doud J, Nador E, Zeitlin L, Pauly M, Moench TR, Brennan M, Whaley KJ, Anderson DJ. EBioMedicine. 2021 Jul; 69:103478. doi: 10.1016/j.ebiom.2021.103478. PMID: 34256345, PMCID: PMC8324805.