{"id":291,"date":"2014-07-09T15:32:57","date_gmt":"2014-07-09T19:32:57","guid":{"rendered":"https:\/\/sites.bu.edu\/bionicpancreas\/?page_id=291"},"modified":"2018-06-28T19:03:45","modified_gmt":"2018-06-28T23:03:45","slug":"publications-2","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/bionicpancreas\/publications-2\/","title":{"rendered":"Publications"},"content":{"rendered":"<h1>Publications<\/h1>\n<div class=\"BU_MGH_CU_Pub_Organization\">\n<h2>Bionic Pancreas Clinical Trials<\/h2>\n<\/div>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/L_pg1.jpg\" alt=\"The Lancet\" width=\"100\" height=\"134\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Home use of a bihormonal bionic pancreas versus insulin pump therapy in adults with type 1 diabetes: a multicentre randomised crossover trial<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2016\/12\/El-Khatib_etal_2016_Lancet.pdf\" target=\"_blank\" title=\"Home use of a bihormonal bionic pancreas versus insulin pump therapy in adults with type 1 diabetes: a multicentre randomised crossover trial\">The Lancet, 2016<\/a><\/p>\n<p><a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(16)32567-3\/supplemental\" target=\"_blank\" title=\"Home use of a bihormonal bionic pancreas versus insulin pump therapy in adults with type 1 diabetes: a multicentre randomised crossover trial - SOM\">Supplemental online material<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/LDE_pg1.jpg\" alt=\"Lancet Cover March 2016\" width=\"100\" height=\"134\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Day and night glycaemic control with a bionic pancreas versus conventional insulin pump therapy in preadolescent children with type 1 diabetes: a randomised crossover trial<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2016\/02\/Russell-Lancet-Diabetes.pdf\" target=\"_blank\" title=\"Day and night glycaemic control with a bionic pancreas versus conventional insulin pump therapy in preadolescent children with type 1 diabetes: a randomised crossover trial\">The Lancet Diabetes and Endocrinology, 2016<\/a><\/p>\n<p><a href=\"\/bionicpancreas\/files\/2016\/04\/Russell-et-al-THELANCETDE-D-15-00403R2-Appendix.pdf\" target=\"_blank\" title=\"Day and night glycaemic control with a bionic pancreas versus conventional insulin pump therapy in preadolescent children with type 1 diabetes: a randomised crossover trial - SOM\">Supplemental online material<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/NEJM_pg1.jpg\" alt=\"NEJM Front Cover\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Outpatient Glycemic Control with a Bionic Pancreas in Type 1 Diabetes<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/Outpatient_Glycemic_Control_NEJM_6_2014.pdf\" target=\"_blank\" title=\"Outpatient Glycemic Control with a Bionic Pancreas in Type 1 Diabetes\">New England Journal of Medicine, 2014<\/a><\/p>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/Outpatient_Glycemic_Control_NEJM_6_2014_supplement.pdf\" target=\"_blank\" title=\"Outpatient Glycemic Control with a Bionic Pancreas in Type 1 Diabetes - SOM\">Supplemental online material<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/JCEM_pg1.jpg\" alt=\"JCEM Cover\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Autonomous and Continuous Adaptation of a Bihormonal Bionic Pancreas in Adults and Adolescents with Type 1 Diabetes.<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/El-Khatib_etal_2014.pdf\" target=\"_blank\" title=\"Autonomous and Continuous Adaptation of a Bihormonal Bionic Pancreas in Adults with Type 1 Diabetes\">J. Clinical Endocrinology and Metabolism, 2014<\/a><\/p>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/SuppMaterials_final.pdf\" target=\"_blank\" title=\"Autonomous and Continuous Adaptation of a Bihormonal Bionic Pancreas in Adults with Type 1 Diabetes - SOM\">Supplemental online material<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/DC_pg1.jpg\" alt=\"Diabetes Care Cover\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Blood Glucose Control in Type 1 Diabetes with a Bihormonal Bionic Endocrine Pancreas<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/RussellEl-Khatib_etal_CL2_Diabetes_Care_2012.pdf\" target=\"_blank\" title=\"Blood Glucose Control in Type 1 Diabetes with a Bihormonal Bionic Endocrine Pancreas\">Diabetes Care, 2012<\/a><\/p>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/DC120071SupplementaryData.pdf\" target=\"_blank\" title=\"Blood Glucose Control in Type 1 Diabetes with a Bihormonal Bionic Endocrine Pancreas - SOM\">Supplemental online material<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/STM_pg1.jpg\" alt=\"Science Translational Medicine Cover\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>A Bihormonal Closed-Loop Artificial Pancreas for Type 1 Diabetes<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/El-Khatib_and_Russell_et_al_Sci_Trans_Med_2010.pdf\" target=\"_blank\" title=\"A Bihormonal Closed-Loop Artificial Pancreas for Type 1 Diabetes\">Science Translational Medicine, 2010<\/a><\/p>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/ElKhatib_and_Russell_et_al_SOM_Sci_Trans_Med_2010.pdf\" target=\"_blank\" title=\"A Bihormonal Closed-Loop Artificial Pancreas for Type 1 Diabetes - SOM\">Supplemental online material<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/01_Russell_and_El-Khatib_et_al_J_Diab_Sci_Tech_2010.jpg\" alt=\"Efficacy Determinants\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Efficacy Determinants of Subcutaneous Microdose Glucagon During Closed-Loop Control<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/Russell_and_El-Khatib_et_al_J_Diab_Sci_Tech_2010.pdf\" target=\"_blank\" title=\"Efficacy Determinants\">J. Diabetes Science and Technology, 2010<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"BU_MGH_CU_Pub_Organization\">\n<h2>CGM Comparison Studies<\/h2>\n<\/div>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/12_Sinha-CGM-lag-analysis-JDST-2017.jpg\" alt=\"CGM Lag Analysis\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>A Comparison of Time Delay in Three Continuous Glucose Monitors for Adolescents and Adults<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2017\/05\/Sinha-CGM-lag-analysis-JDST-2017.pdf\" target=\"_blank\" title=\"A Comparison of Time Delay in Three Continuous Glucose Monitors for Adolescents and Adults\">J. Diabetes Science and Technology, 2017<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/02_Comparative-Accuracy-Meters-Ekhlaspour-J-Diabetes-Sci-Technol-2016.jpg\" alt=\"Diabetes Science and Technology Cover\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Comparative Accuracy of 17 Point-of-Care Glucose Meters<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2016\/11\/Comparative-Accuracy-Meters-Ekhlaspour-J-Diabetes-Sci-Technol-2016.pdf\" target=\"_blank\" title=\"Comparative Accuracy of 17 Point-of-Care Glucose Meters\">J. Diabetes Science and Technology, 2016<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/03_G4__Enlite__Nav_comparison_Damiano_JDST_2014.jpg\" alt=\"Diabetes Science and Technology Cover\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>A Comparative Effectiveness Analysis of Three Continuous Glucose Monitors: The Navigator, G4 Patinum, and Enlite<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/G4__Enlite__Nav_comparison_Damiano_JDST_2014.pdf\" target=\"_blank\" title=\"A Comparative Effectiveness Analysis of Three Continuous Glucose Monitors: The Navigator, G4 Platinum, and Enlite\">J. Diabetes Science and Technology, 2014<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/04_DamianoCGM2013.jpg\" alt=\"Diabetes Science and Technology Cover\" alt=\"Diabetes Care Cover\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Comparative Effectiveness Analysis of Three Continuous Glucose Monitors<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/DamianoCGM2013.pdf\" target=\"_blank\" title=\"Comparative Effectiveness Analysis of Three Continuous Glucose Monitors\">Diabetes Care, 2013 (includes supplement)<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"BU_MGH_CU_Pub_Organization\">\n<h2>Pre-Clinical Studies<\/h2>\n<\/div>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/05_Closed-loop_El-Khatib_J_Diab_Sci_Tech_2009.jpg\" alt=\"A Feasibility Study\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>A Feasibility Study of Bihormonal Closed-Loop Blood Glucose Control Using Dual Subcutaneous Infusion of Insulin and Glucagon in Ambulatory Diabetic Swine<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/Closed-loop_El-Khatib_J_Diab_Sci_Tech_2009.pdf\" target=\"_blank\" title=\"A Feasibility Study\">J. Diabetes Science and Technology, 2009<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/06_Closed-loop_El-Khatib_J_Diab_Sci_Tech_2007.jpg\" alt=\"Adaptive Closed-Loop Control\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Adaptive Closed-Loop Control Provides Blood-Glucose Regulation Using Dual Subcutaneous Insulin and Glucagon Infusion in Diabetic Swine<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/Closed-loop_El-Khatib_J_Diab_Sci_Tech_2007.pdf\" target=\"_blank\" title=\"Adaptive Closed-Loop Control\">J. Diabetes Science and Technology, 2007<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/07_Pharm_stability_glucagon_El-Khatib_Diab_Tech_Ther_2007.jpg\" alt=\"Pharmacodynamics and Stability of Subcutaneously Infused Glucagon\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Pharmacodynamics and Stability of Subcutaneously Infused Glucagon in a Type 1 Diabetic Swine Model In Vivo<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/Pharm_stability_glucagon_El-Khatib_Diab_Tech_Ther_2007.pdf\" target=\"_blank\" title=\"Pharmacodynamics and Stability of Subcutaneously Infused Glucagon\"\">Diabetes Technology and Therapeutics, 2007<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"BU_MGH_CU_Pub_Organization\">\n<h2>Review and Commentary<\/h2>\n<\/div>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/08_Design-Considerations-for-Aritifical-Pancreas-Pivotal-Studies.jpg\" alt=\"Progress of Artificial Pancreas Devices\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Design Considerations for Artificial Pancreas Pivotal Studies<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2017\/03\/Design-Considerations-for-Aritifical-Pancreas-Pivotal-Studies.pdf\" target=\"_blank\" title=\"Design Considerations for Artificial Pancreas Pivotal Studies\"\">Diabetes Care, 2016<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2018\/06\/outcomes.png\" alt=\"Outcome Measures for AP Clinical Trials\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2018\/06\/Outcomes-AP-studies-consensus-Maahs-Diab-Care-2016.pdf\" target=\"_blank\" title=\"Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report\">Diabetes Care, 2016<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/09_Outpatient-AP-review-SJR-Curr-Opin-Diab-Endo-Obes-4-2015.jpg\" alt=\"Progress of Artificial Pancreas Devices\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Progress of Artificial Pancreas Devices Towards Clinical Use: the First Outpatient Studies<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2015\/04\/Outpatient-AP-review-SJR-Curr-Opin-Diab-Endo-Obes-4-2015.pdf\" target=\"_blank\" title=\"Progress of Artificial Pancreas Devices\"\">Current Opinion in Endocrinology, Diabetes and Obesity, 2015<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/10_Future-of-care-for-diabetes-Nathan-and-Russell-CMAJ-2013.jpg\" alt=\"The Future of Care for Type 1 Diabetes\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>The Future of Care for Type 1 Diabetes<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2014\/08\/Future-of-care-for-diabetes-Nathan-and-Russell-CMAJ-2013.pdf\" target=\"_blank\" title=\"The Future of Care for Type 1 Diabetes\"\">Canadian Medical Association Journal, 2013<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n<div class=\"pub_wrapper\">\n<div class=\"pub_icon\">\n      <img loading=\"lazy\" src=\"\/bionicpancreas\/files\/2017\/05\/11_CGM_killer_app_Russell_Diab_Sci_Technol_2008.jpg\" alt=\"Continuous Glucose Monitor Awaits Killer App\" width=\"100\" height=\"150\" style=\"border: 5px solid black;\" \/>\n   <\/div>\n<div class=\"pub_description\">\n<h3>Continuous Glucose Monitoring Awaits Its &#8220;Killer App&#8221;<\/h3>\n<p><a href=\"\/bionicpancreas\/files\/2014\/07\/CGM_killer_app_Russell_Diab_Sci_Technol_2008.pdf\" target=\"_blank\" title=\"Continuous Glucose Monitoring Awaits Its \"Killer App\"\">J. Diabetes Science and Technology, 2008<\/a><\/p>\n<\/p><\/div>\n<\/div>\n<hr \/>\n","protected":false},"excerpt":{"rendered":"<p>Publications Bionic Pancreas Clinical Trials Home use of a bihormonal bionic pancreas versus insulin pump therapy in adults with type 1 diabetes: a multicentre randomised crossover trial The Lancet, 2016 Supplemental online material Day and night glycaemic control with a bionic pancreas versus conventional insulin pump therapy in preadolescent children with type 1 diabetes: a [&hellip;]<\/p>\n","protected":false},"author":8928,"featured_media":0,"parent":0,"menu_order":6,"comment_status":"closed","ping_status":"closed","template":"page-templates\/no-sidebars.php","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/bionicpancreas\/wp-json\/wp\/v2\/pages\/291"}],"collection":[{"href":"https:\/\/sites.bu.edu\/bionicpancreas\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/bionicpancreas\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/bionicpancreas\/wp-json\/wp\/v2\/users\/8928"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/bionicpancreas\/wp-json\/wp\/v2\/comments?post=291"}],"version-history":[{"count":50,"href":"https:\/\/sites.bu.edu\/bionicpancreas\/wp-json\/wp\/v2\/pages\/291\/revisions"}],"predecessor-version":[{"id":2607,"href":"https:\/\/sites.bu.edu\/bionicpancreas\/wp-json\/wp\/v2\/pages\/291\/revisions\/2607"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/bionicpancreas\/wp-json\/wp\/v2\/media?parent=291"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}