{"id":98,"date":"2019-06-30T09:31:24","date_gmt":"2019-06-30T13:31:24","guid":{"rendered":"https:\/\/sites.bu.edu\/biomicroscopy\/?page_id=98"},"modified":"2026-03-22T13:57:17","modified_gmt":"2026-03-22T17:57:17","slug":"research","status":"publish","type":"page","link":"https:\/\/sites.bu.edu\/biomicroscopy\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n
\"\"Far-field ultrasound beamforming<\/h5>\n

Combined transmit\/receive plane-wave decomposition enables versatile ultrasound imaging with compressed data. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Spatially variant deconvolution<\/h5>\n

Modal deconvolution is performed by decomposition of PSFs into eigenmodes with spatially varying weights. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Coherent background subtraction<\/h5>\n

Coherent background subtraction (CBS) improves SNR in camera-based pump-probe imaging. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Adaptive ultrasound beamforming<\/h5>\n

Improved ultrasound images are obtained by suppression of incoherent clutter and noise. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"High contrast voltage imaging<\/h5>\n

Genetically encoded voltage indicators (GEVIs) are imaged at kilohertz rates by targeted-illumination and confocal microscopy. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Deblurring by pixel reassignment<\/h5>\n

General algorithm for image sharpening is based on pixel reassignment. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Imaging at trillion frames per second<\/h5>\n

Single-shot non-synchronous array photography (SNAP) is performed with time-to-angle multiplexing. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Ultrafast laser scanning<\/h5>\n

A passive scan multiplier unit enables a galvanometer to perform high throughput ultrafast laser scanning beyond the inertia limit. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Laser speckle contrast imaging<\/h5>\n

Multifocus laser speckle contrast imaging (LSCI) reveals mixed blood-flow dynamics in the brain. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Ultrasound phase-contrast imaging<\/h5>\n

Differential phase contrast using the memory effect enables a standard US imaging device to reveal subsurface speed-of-sound variations in real time. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Widefield multifocus imaging<\/h5>\n

High-contrast multifocus microscopy is performed with a single camera and versatile z-splitter prism. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Retroillumination corneal imaging<\/h5>\n

Widefield corneal imaging is performed by oblique retroillumination microscopy. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Reverberation multiphoton microscopy<\/h5>\n

Quasi-simultaneous multiplane imaging is performed using temporal multiplexing with a reverberation loop. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Multi-Z confocal microscopy<\/h5>\n

Simultaneous multiplane imaging is performed over large fields of view at rates up to a kilohertz. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Compressive flow cytometry<\/h5>\n

High-throughput flow cytometry is performed with matched-filter compressive imaging. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Transcranial retinal imaging<\/h5>\n

Transcranial retinal imaging is a method for transilluminating the ocular fundus (i.e. the back of the eye). Read more…<\/a><\/p>\n

 <\/td>\n<\/tr>\n

\n
\"\"Extended-depth-of-field microscopy<\/h5>\n

Computational and physical variations of extended-depth-of-field (EDOF) imaging lead to increased contrast. Read more…<\/a><\/p>\n

 <\/td>\n<\/tr>\n

\n
\"\"Oblique back-illumination microscopy<\/h5>\n

OBM provides DIC-like phase contrast in arbitrarily thick tissue.\u00a0 The technique is simple, fast, and can be implemented in camera- or scanning-based configurations. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Active illumination microscopy<\/h5>\n

AIM significantly increases the dynamic range and enhances the weak-signal sensitivity of a scanning fluorescence microscope, without loss of information. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Imaging through complex media<\/h5>\n

Variants of adaptive optics are used to improve imaging through an aberrating screen or to control spectral decorrelation through a scattering medium. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Imaging through a single optical fiber<\/h5>\n

Self-luminous objects are imaged through a single optical fiber using spread-spectral encoding. The method contains no moving parts and is insensitive to fiber bending. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Partitioned aperture wavefront imaging<\/h5>\n

Single-shot, quantitative phase imaging using a specially constructed lens.\u00a0 Our technique is achromatic, polarization independent, and light-efficient. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"HiLo microscopy<\/h5>\n

HiLo microscopy enables a standard widefield fluorescence or reflectance microscope to provide optical sectioning by using two images acquired with uniform and non-uniform (or “structured”) illumination. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Differential aberration imaging<\/h5>\n

DAI enables multiphoton contrast enhancement by near-instantaneously acquiring non-aberrated and aberrated images. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Dynamic speckle illumination microscopy<\/h5>\n

DSI microscopy enables a standard widefield fluorescence microscope to provide optical sectioning by using randomly changing speckle illumination. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Autoconfocal microscopy<\/h5>\n

Autoconfocal microscopy (ACM) enables a two-photon excited fluorescence microscope to produce simultaneous phase contrast by using a virtual pinhole in the transmission direction. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Graded field microscopy<\/h5>\n

Graded field microscopy reveals phase gradients in a sample by combining oblique illumination with oblique detection. The resulting image resembles DIC. Read more…<\/a><\/td>\n<\/tr>\n

\n
\"\"Nonlinear microscopy<\/h5>\n

Nonlinear optical microscopy provides contrast based on a nonlinear interaction of light and matter. Examples include two-photon excited fluorescence (TPEF) and second harmonic generation (SHG) microscopy. Read more…<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

<\/h5>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Far-field ultrasound beamforming Combined transmit\/receive plane-wave decomposition enables versatile ultrasound imaging with compressed data. Read more… Spatially variant deconvolution Modal deconvolution is performed by decomposition of PSFs into eigenmodes with spatially varying weights. Read more… Coherent background subtraction Coherent background subtraction (CBS) improves SNR in camera-based pump-probe imaging. Read more… Adaptive ultrasound beamforming Improved ultrasound […]<\/p>\n","protected":false},"author":16427,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"page-templates\/profiles.php","meta":[],"_links":{"self":[{"href":"https:\/\/sites.bu.edu\/biomicroscopy\/wp-json\/wp\/v2\/pages\/98"}],"collection":[{"href":"https:\/\/sites.bu.edu\/biomicroscopy\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.bu.edu\/biomicroscopy\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/biomicroscopy\/wp-json\/wp\/v2\/users\/16427"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.bu.edu\/biomicroscopy\/wp-json\/wp\/v2\/comments?post=98"}],"version-history":[{"count":50,"href":"https:\/\/sites.bu.edu\/biomicroscopy\/wp-json\/wp\/v2\/pages\/98\/revisions"}],"predecessor-version":[{"id":842,"href":"https:\/\/sites.bu.edu\/biomicroscopy\/wp-json\/wp\/v2\/pages\/98\/revisions\/842"}],"wp:attachment":[{"href":"https:\/\/sites.bu.edu\/biomicroscopy\/wp-json\/wp\/v2\/media?parent=98"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}