URBAN ARCH Boston Cohort
The 4F study will continue to follow and expand (from 250 to 400 participants) the existing Boston Cohort in order to 1) test the associations between alcohol (and illicit drugs and polypharmacy) and falls (fractures secondarily), and 2) test the associations between alcohol (and illicit drugs and polypharmacy) and acute healthcare utilization (emergency department use and hospitalization for falls and fractures). This knowledge will serve to inform the development of ways to identify, prevent and manage falls, fractures, frailty and functional impairment among people living with HIV.
Richard Saitz, MD, MPH
Chair, Department of Community Health Sciences; Professor of Community Health Sciences and Medicine, Boston University Schools of Public Health and Medicine (BUSPH/BUSM)
Traci Green, PhD, MSc
Associate Professor of Emergency Medicine and Community Health Sciences, BUSM/BUSPH
Alan Jette, PT, PhD
Professor of Health Policy and Management, BUSPH
Alexander Walley, MD, MSc
Assistant Professor of Medicine, BUSM
Recruitment Site: Boston Medical Center/Boston University School of Medicine, Boston, MA, USA.
First Cycle (2011-2016) Original Boston Cohort Grant Title: Addressing Alcohol/HIV Consequences in Substance Dependence
The original Boston Cohort was a prospective observational investigation of the effects of alcohol on people with HIV infection who may be affected by multiple substances of abuse (i.e. other drugs). It is now being continued as the 4F study. The Cohort also served as a platform for intervention trials. In its initial implementation, the project was designed to answer two research questions: Is unhealthy alcohol use associated with osteopenia in HIV-infected adults and does buprenorphine reduce heavy alcohol use?