URBAN ARCH Boston Cohort

Grant Title: URBAN ARCH (5/5) Boston Cohort – Alcohol And HIV-Associated Comorbidity and Complications: Frailty, Functional Impairment, Falls, and Fractures (The 4F Study)

The 4F study will continue to follow and expand (from 250 to 400 participants) the existing Boston Cohort in order to 1) test the associations between alcohol (and illicit drugs and polypharmacy) and falls (fractures secondarily), and 2) test the associations between alcohol (and illicit drugs and polypharmacy) and acute healthcare utilization (emergency department use and hospitalization for falls and fractures). This knowledge will serve to inform the development of ways to identify, prevent and manage falls, fractures, frailty and functional impairment among people living with HIV.

Principal Investigator:

Richard Saitz, MD, MPH
Chair, Department of Community Health Sciences; Professor of Community Health Sciences and Medicine, Boston University Schools of Public Health and Medicine (BUSPH/BUSM)

Study Contact:

Seville Meli, MPH (seville@bu.edu)
Director of Research Operations, Community Health Sciences Department, BUSPH

Mariana Krueger, MS (mkrueger@bu.edu)
Research Project Manager, Community Health Sciences Department, BUSPH

Study Investigators:

Traci Green, PhD, MSc
Associate Professor of Emergency Medicine and Community Health Sciences, BUSM/BUSPH

Alan Jette, PT, PhD
Professor of Health Policy and Management, BUSPH

Margaret Sullivan, MD
Assistant Professor of Medicine, BUSM

Alexander Walley, MD, MSc
Assistant Professor of Medicine, BUSM

Study progress: The 4F study is expected to begin participant recruitment and assessments in 2017. For more information, click here.

Recruitment SiteBoston Medical Center/Boston University School of Medicine, Boston, MA, USA.

First Cycle (2011-2016) Original Boston Cohort Grant Title: Addressing Alcohol/HIV Consequences in Substance Dependence

The original Boston Cohort was a prospective observational investigation of the effects of alcohol on people with HIV infection who may be affected by multiple substances of abuse (i.e. other drugs). It is now being continued as the 4F study. The Cohort also served as a platform for intervention trials. In its initial implementation, the project was designed to answer two research questions: Is unhealthy alcohol use associated with osteopenia in HIV-infected adults and does buprenorphine reduce heavy alcohol use?

Affiliated Studies:

Internet-Based Video-Conferencing to Address Alcohol Use And Pain Among Heavy Drinkers in HIV-Care

Click here for additional information about the original Boston Cohort. Click here to see baseline characteristics.