Tagged: Valproate

Reopening Our Critical Period as Adults

February 28th, 2014 in Article, News 0 comments

Ever wonder why children can learn certain things, such as languages, faster than adults? There is a time in every human’s life called the critical period, and it takes place during the most intense period of development, childhood. ┬áDuring this time a child’s brain has high neuroplasticity, almost like a sponge. Many new pathways are formed as the child experiences new things. It has always been believed that when our critical period ends it never comes back but recent study has been done with the drug Valproate that increased neural plasticity in adults and may have reopened this critical period.

Valproate is a drug most commonly used for bipolar disorder and epilepsy. It is also known to inhibit an enzyme called histone- deacetylase, or HDAC. HDAC is an enzyme in the brain that slows down neural plasticity. Inhibition of this enzyme by Valproate allows the reopening of pathways in the brain, increasing neuroplasticity, thus reopening the critical period.

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