Selected News from our Group

UROP Symposium presentation

October 20th, 2017

Sweta Duraiswamy gave a presentation on her summer work investigating DUX4 function and structure at the BU undergraduate research symposium.

New manuscript submitted

August 15th, 2017

We’ve submitted a new manuscript for publication in which we describe our studies of pathogenesis in laminin-alpha2-deficiency (MDC1A). This study has a particular focus on aberrant intracellular signaling, including p53, sirtuins, and protein kinases.

Jeff publishes Canvasback duck article

August 1st, 2017

Jeff has published this article in the journal Bird Observer in which he discusses the history and current status of Canvasback Ducks in New England. The work arose from his observations at Fresh Pond in Cambridge, Massachusetts.

UROP student begins

June 6th, 2017

Swetha Duraiswamy has begun her summer research project on DUX4-mediated mechanisms of pathology. She is supported by the Undergraduate Research Opportunities Program at Boston University.

Boston’s March for Science!

April 22nd, 2017

It was an inspiring day at today’s Boston March for Science! Tens of thousands braved the cold and rainy weather, including hundreds and hundreds of children who made good use of the many kids-themed activity tables. Former EPA administrator (and Boston native) Gina McCarthy gave an especially motivating and fiery speech. Very glad I could join everyone there!

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UROP fellowship to Swetha Duraiswamy

March 25th, 2017

The Undergraduate Research Opportunities Program at Boston University has awarded a fellowship to Swetha Duaraiswamy to support her summer work in our laboratory. Congrats!

Join Jeff at the Boston March for Science

March 11th, 2017

April 22, 2017 — if you can’t make it to D.C., then consider joining New England scientists and supporters of science at the Boston Common from 1pm – 4pm. Details are here:  marchforscienceboston.com

New summer student

February 27th, 2017

Swetha Duraiswamy, who is in BU’s seven year Liberal Arts/Medical Education program, will be joining us this summer as an undergraduate researcher.  Swetha has previous research lab experience at Brown University.

FSH Society grant

February 11th, 2017

The FSH Society has made an award to support the work of Dr. Sachiko Homma on DUX4-induced mechanisms of pathogenesis.

Myogenesis and FSHD paper published

December 2nd, 2016

Our new paper has been published by Skeletal Muscle. We focus on reorganization of nuclear bodies (nucleoli, PML bodies, SC35 speckles) during normal myogenesis and on how expression of DUX4 affects these nuclear structures that are key to regulation of gene expression. The paper is available here.

FSHD paper accepted for publication

November 15th, 2016

Homma, S., Beermann, M.L., Yu, B., Boyce, F.M., and Miller, J.B. (2016) Nuclear bodies reorganize during myogenesis and are differentially disrupted by expression of FSHD-associated DUX4. Skeletal Muscle (in press)

Work presented at FSHD conference

November 10th, 2016

Sachiko Homma, Mary Lou Beermann, and Bryant Yu presented our work on how nuclear body organization is affected by DUX4 expression at the FSHD Research Connects Symposium.

Abstract submitted for FSHD conference

October 18th, 2016

We’ve submitted an abstract for presentation at the FSHD Research Connects Conference which will be in Boston on November 10-11. The abstract describes our study of DUX4 and nuclear bodies, with Sachiko Homma, Mary Lou Beermann, Bryant YU, our MGH collaborator Rick Boyce, and Jeff as authors.

New research paper submitted

August 12th, 2016

We’ve submitted a new research paper for publication that focuses on nuclear bodies in myogenesis and muscle disease. Authors include Sachiko Homma, Mary Lou Beermann, Bryant Yu, our MGH collaborator Rick Boyce, and Jeff.

Jeff publishes “Birds & Bats” article

July 30th, 2016

Jeff has published this field note in the journal Bird Observer in which he discusses the reciprocal predator-prey relationships between birds and bats. The article arose from an observation of a Red-tailed Hawk attempting to capture a bat in Mt. Auburn Cemetery.

Bryant Yu joins our group

June 5th, 2016

Bryant Yu, a recent BU graduate, has joined our group as a research technician.  He will take up projects on MDC1A, LGMD, and FSHD.

UROP award for Kevin Liu

April 24th, 2016

The BU Undergraduate Research Opportunities Program has given an award to Kevin Liu to support his summer research work in our lab.  Congratulations Kevin!

Kevin Liu to join us this summer

February 18th, 2016

Kevin Liu, a freshman in BU’s seven year Liberal Arts/Medical Education program, will be joining us this summer as an undergraduate researcher.  Kevin has previous research lab experience at Stanford.

Undergraduate summer research

January 19th, 2016

We have an opening for an undergraduate to join our laboratory for the summer of 2016.  This position will be sponsored through the BU Undergraduate Research Opportunities Program (UROP).  You can see our post under the heading “Cell Biology of Muscle Disease” on the opportunities page of the UROP website.

New collaboration in progress

December 15th, 2015

Our new collaboration with Dr. Hiroaki Mitshuhashi of Tokai University in Tokyo, Japan is moving forward. Together, we will be examining how aberrant expression of the DUX4 protein may lead to pathology in FSHD.

Dr. Homma presents at FSHD Conference

October 5th, 2015

Our colleague, Dr. Sachiko Homma presented her work on DUX4 structure and pathogenesis at the FSHD International Conference. Co-authors were our MGH colleague, Dr. Rick Boyce, and Jeff

Abstract for FSHD Conference

September 18th, 2015

We have submitted an abstract for presentation at the FSHD International Consortium conference to be held in Boston on October 5-6.

Two abstracts for Ottawa meeting

July 28th, 2015

Our lab group has submitted two abstracts for presentation at the Ottawa neuromuscular disease meeting in September.  One abstract focuses on FSHD and the second is on MDC1A.

FSH Society grant to Dr. Homma

June 26th, 2015

The FSH Society has announced that they have awarded a new research grant to our colleague Dr. Sachiko Homma.  This award will support her work on mechanisms of DUX4-mediated pathology in facioscapulohumeral muscular dystrophy.

Summer researchers begin

June 1st, 2015

Emily Misnick, supported by a Clare Booth Luce award, and Bryant Yu, supported by an award from the BU Undergraduate Research Opportunities Program, have begun their summer projects in our lab.  Welcome!