Sweta Duraiswamy gave a presentation on her summer work investigating DUX4 function and structure at the BU undergraduate research symposium.
We’ve submitted a new manuscript for publication in which we describe our studies of pathogenesis in laminin-alpha2-deficiency (MDC1A). This study has a particular focus on aberrant intracellular signaling, including p53, sirtuins, and protein kinases.
Jeff has published this article in the journal Bird Observer in which he discusses the history and current status of Canvasback Ducks in New England. The work arose from his observations at Fresh Pond in Cambridge, Massachusetts.
Swetha Duraiswamy has begun her summer research project on DUX4-mediated mechanisms of pathology. She is supported by the Undergraduate Research Opportunities Program at Boston University.
It was an inspiring day at today’s Boston March for Science! Tens of thousands braved the cold and rainy weather, including hundreds and hundreds of children who made good use of the many kids-themed activity tables. Former EPA administrator (and Boston native) Gina McCarthy gave an especially motivating and fiery speech. Very glad I could join everyone there!
The Undergraduate Research Opportunities Program at Boston University has awarded a fellowship to Swetha Duaraiswamy to support her summer work in our laboratory. Congrats!
April 22, 2017 — if you can’t make it to D.C., then consider joining New England scientists and supporters of science at the Boston Common from 1pm – 4pm. Details are here: marchforscienceboston.com
Swetha Duraiswamy, who is in BU’s seven year Liberal Arts/Medical Education program, will be joining us this summer as an undergraduate researcher. Swetha has previous research lab experience at Brown University.
The FSH Society has made an award to support the work of Dr. Sachiko Homma on DUX4-induced mechanisms of pathogenesis.
Our new paper has been published by Skeletal Muscle. We focus on reorganization of nuclear bodies (nucleoli, PML bodies, SC35 speckles) during normal myogenesis and on how expression of DUX4 affects these nuclear structures that are key to regulation of gene expression. The paper is available here.
Homma, S., Beermann, M.L., Yu, B., Boyce, F.M., and Miller, J.B. (2016) Nuclear bodies reorganize during myogenesis and are differentially disrupted by expression of FSHD-associated DUX4. Skeletal Muscle (in press)
Sachiko Homma, Mary Lou Beermann, and Bryant Yu presented our work on how nuclear body organization is affected by DUX4 expression at the FSHD Research Connects Symposium.
We’ve submitted an abstract for presentation at the FSHD Research Connects Conference which will be in Boston on November 10-11. The abstract describes our study of DUX4 and nuclear bodies, with Sachiko Homma, Mary Lou Beermann, Bryant YU, our MGH collaborator Rick Boyce, and Jeff as authors.
We’ve submitted a new research paper for publication that focuses on nuclear bodies in myogenesis and muscle disease. Authors include Sachiko Homma, Mary Lou Beermann, Bryant Yu, our MGH collaborator Rick Boyce, and Jeff.
Jeff has published this field note in the journal Bird Observer in which he discusses the reciprocal predator-prey relationships between birds and bats. The article arose from an observation of a Red-tailed Hawk attempting to capture a bat in Mt. Auburn Cemetery.
Bryant Yu, a recent BU graduate, has joined our group as a research technician. He will take up projects on MDC1A, LGMD, and FSHD.
The BU Undergraduate Research Opportunities Program has given an award to Kevin Liu to support his summer research work in our lab. Congratulations Kevin!
Kevin Liu, a freshman in BU’s seven year Liberal Arts/Medical Education program, will be joining us this summer as an undergraduate researcher. Kevin has previous research lab experience at Stanford.
We have an opening for an undergraduate to join our laboratory for the summer of 2016. This position will be sponsored through the BU Undergraduate Research Opportunities Program (UROP). You can see our post under the heading “Cell Biology of Muscle Disease” on the opportunities page of the UROP website.
Our new collaboration with Dr. Hiroaki Mitshuhashi of Tokai University in Tokyo, Japan is moving forward. Together, we will be examining how aberrant expression of the DUX4 protein may lead to pathology in FSHD.
Our colleague, Dr. Sachiko Homma presented her work on DUX4 structure and pathogenesis at the FSHD International Conference. Co-authors were our MGH colleague, Dr. Rick Boyce, and Jeff
We have submitted an abstract for presentation at the FSHD International Consortium conference to be held in Boston on October 5-6.
Our lab group has submitted two abstracts for presentation at the Ottawa neuromuscular disease meeting in September. One abstract focuses on FSHD and the second is on MDC1A.
The FSH Society has announced that they have awarded a new research grant to our colleague Dr. Sachiko Homma. This award will support her work on mechanisms of DUX4-mediated pathology in facioscapulohumeral muscular dystrophy.
Emily Misnick, supported by a Clare Booth Luce award, and Bryant Yu, supported by an award from the BU Undergraduate Research Opportunities Program, have begun their summer projects in our lab. Welcome!