People

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Principal Investigators

Graduate Students

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    Hannah Axten

    (Neurobiology)

    Education: B.S. in Neuroscience from Boston University
    Thesis Research: Hannah studies the transcription factor Foxr1 and its role in neurodevelopment. A human patient with a heterozygous mutation in FOXR1 displays developmental delay, progressive brain atrophy and microcephaly. Mice null for the Foxr1 gene recapitulate aspects of the human patient phenotype.
    Hobbies: Hannah enjoys spending time with her cat, biking, and playing music in a band

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    Sabrina Kistler

    (Biomolecular Pharmacology)

    Education: B.S. in Biology from Penn State University
    Thesis Research: Sabrina’s research is focused on understanding the role of APOER2 splicing and its relevance to Alzheimer’s disease. She is using both human brain samples and mouse models to investigate how APOER2 splice variants are connected to disease progression.
    Hobbies: Sabrina enjoys baking, puzzles, reading, and watching The Real Housewives

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    Channa Bao

    (Biomolecular Pharmacology/ Biogen)

    Education: B.S. in Neuroscience and Behavior from Columbia University
    Thesis Research: Channa’s research interests are in neuropharmacology and neurobiology. She is interested in investigating the molecular and cellular processes that underpin neurological disorders with the goal of characterizing novel therapeutic targets or strategies that can impact disease pathophysiology.
    Hobbies: Channa likes drawing, travelling, and her pet rabbits

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    Mingqi Sha

    (Neurobiology)

    Education: B.S. in Biology from Brandeis University
    Thesis Research: Mingqi’s research interests are investigating the cellular and molecular mechanisms regulating neurological and neurodevelopmental disorders. She is interested in studying gene/protein regulators and understanding what their roles are in the biological or pathogenic pathway.
    Hobbies: Mingqi enjoys jogging, playing the piano, traveling and eating.

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    Negar Rahmani

    (Graduate Program in Neuroscience)

    Education: B.S. in Nursing from Qazvin University of Medical Sciences, M.S. in Neuroscience from University of Rhode Island
    Thesis Research: Negar’s research focuses on understanding the biology of resilient Alzheimer’s disease (AD) genes, such as Reelin and the recently identified RELN-COLBOS mutation. She is interested in investigating the functional consequences of APOER2 splice variants in relation to Reelin binding and signaling, and their impact on AD risk.
    Hobbies: In her free time, she enjoys spending time with her cat, practicing yoga, and weightlifting.

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    Jared Tague

    (Biology)

    Education: B.S. in Biology from University of Massachusetts Lowell with a Minor in Psychology
    Thesis Research: Jared’s research focuses on purifying Reelin and ApoE to investigate their interactions with the transmembrane receptors APOER2 and VLDLR, along with their splice variants, aiming to understand their roles in receptor-ligand binding dynamics.
    Hobbies: In his free time, he enjoys reading for his book club, bar trivia, poker with his friends, and hanging out with his cat.

    Alumni Graduate Students/Postdocs

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    Gavin Lagani, Ph.D.

    Graduate Program – Neurobiology

    Consultant, Acsel Health

    Thesis: Elucidating the molecular mechanisms of acute reelin signaling in regulating the proteome and actin cytoskeleton during neurodevelopment
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    Christina Gallo, Ph.D.

    Graduate Program – Biomolecular Pharmacology

    Senior Scientist, Biogen

    Thesis: Alternative splicing of APOER2 across the evolution of the vertebrate brain and its relevance to Alzheimer’s disease
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    Shawna Henry, Ph.D.

    Graduate Program – Cell and Molecular Biology

    Senior Scientist, City Therapeutics

    Thesis: Characterization and exploiting the amyloid precursor protein – Mint1 interaction as an Alzheimer’s disease therapeutic target
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    Keri Omuro, Ph.D.

    Graduate Program – Graduate Program in Neuroscience

    Institutional Data Analyst, College Kickstart

    Thesis: Identification of novel Apolipoprotein E receptor 2 splice variants and their role in synaptic transmission
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    Andressa Mota, Ph.D.

    Graduate Program – MCBB

    Scientist, Berg Health

    Thesis: Forkhead Box R1-mediated stress response linked to a case of human microcephaly and progressive brain atrophy
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    Amy Ying Lin, Ph.D.

    Graduate Program – Biomolecular Pharmacology

    Scientist II, Intra-Cellular Therapies

    Thesis: Autism associated Mint2 mutation alters neurexin trafficking and synaptic function
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    Greg Dillon, Ph.D.

    Graduate Program – Neurobiology

    Scientist II, Biogen

    Thesis: Microtubule plus-end binding protein CLASP2 in neural development
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    Sarah Sulllivan, Ph.D.

    Graduate Program – Cell and Molecular Biology

    Principal Scientist, Vertex Pharmaceuticals

    Thesis: Mint-dependent regulation of amyloid precursor protein trafficking and processing in neurons
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    Jeremy Chaufty, Ph.D.

    Graduate Program – Neurobiology

    Principal Scientist, UCB

    Thesis: Protein sorting and trafficking by neuronal adaptor proteins: characterization of a conserved dendritic targeting motif on Kv4 channels and endocytic sorting of APP by Mint2/X11L
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    Maria F. Matos, Ph.D.

    Postdoctoral Associate

    Senior Project Manager, Yale School of Medicine

    Autoinhibition of Mint1 regulates APP binding and processing

    Undergraduate Students (Current)

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    Marcus Kankkunen

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    Anna-Maria Marinescu

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    Margo Dowgiewicz

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    Arya Gupta

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    Inna Kuznetsova

Undergraduate Students (Past)

Sahana Natarajan (Research Associate I at the Broad Institute)
Anna Natrakul (Clinical Care Technician at Tufts Medical Center)
Emily Kim (Masters Student, Boston University)
Shivani Raghunath Rao (Medical Student, Duke Medical School, Singapore)
Feodora Bertherat (Graduate Student, Oxford University)
Lauren Scrandis (Student Nurse University of Maryland Baltimore Washington Medical Center)
Alice Chiang (Graduate Student, Knoxville Master’s Physician Assistant Studies Program)
Taylor Hall (SURF Student – 2017; Medical Student, UCSF)
Julia Hacker (Research Technician, Children’s Hospital PA)
Connor Kenny (Graduate Student, MIT)
Christine Learned (Medical Student, Albany Medical College)
Elias Fong (Data Strategy and Design at ACEA)
Camila Tyminski (Medical Student, Boston University School of Medicine)
Alicia Dupre (Medical Student, Boston University School of Medicine)
Kirsten Kuhn (Undergraduate, Boston University)
Tammo Heinrich (High School Student, Germany)
Melissa Cao (RISE student – 2015)
Sheila Okere (SURF Student – 2014)
Sebastian Gil (SURF Student – 2013)
John Kambouris (Intern-Biomaterials Research, Bioventus)
Hena Choudhry (Graduate Student, Columbia University)
Josefa Sullivan (Graduate Student, Icahn School of Medicine at Mount Sinai)
Christine Stuart (Research Assistant, National Institute of Health)
Domenic Filingeri (Medical Student, Boston University School of Medicine)
Alexander Moise (Medical Student, University of Cinninnati)
Dana Simmons (Graduate Student, University of Chicago)
Anthony Esposito (Medical Student, Boston University School of Medicine)
Samantha Bettencourt (Account Manager, Caradigm)
Han Park (Graduate Student, Postech University, Korea)
Felecia Marottoli (Graduate Student, University of Illinois, Chicago)