The Bionic Pancreas

The Bionic Pancreas currently uses three system components to implement automated control of blood glucose.

  1. The Dexcom G4 Platinum Continuous Glucose Monitor (CGM) measures interstitial fluid glucose every 5 minutes as an estimation of blood glucose.
  2. A glucose sensor is inserted into the body using an automated injector. A transmitter is then attached to enable transmission of glucose data wirelessly to the Dexcom receiver.

  3. The iPhone streams the glucose data from the CGM every 5 minutes and uses a mathematical algorithm to determine the appropriate dosing response. That means the Bionic Pancreas makes 288 dosing decisions per day, 7 days per week, 365 days per year.
  4. The iPhone is connected by cable to the Dexcom G4 receiver and runs a custom app that acts upon the glucose data by computing how much insulin or glucagon to deliver every 5 minutes. The app then sends these dosing instructions via Bluetooth to two pumps.

  5. The two Tandem t:slim pumps, one filled with insulin and the other with glucagon, receive dosing instructions from the iPhone every 5 minutes via Bluetooth. The doses of these two hormones are used to regulate blood glucose.
  6. The pumps deliver the insulin and glucagon doses subcutaneously through separate infusion sets.