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The Bionic Pancreas
The Bionic Pancreas currently uses three system components to implement automated control of blood glucose.
- The Dexcom G4 Platinum Continuous Glucose Monitor (CGM) measures interstitial fluid glucose every 5 minutes as an estimation of blood glucose.
- The iPhone streams the glucose data from the CGM every 5 minutes and uses a mathematical algorithm to determine the appropriate dosing response. That means the Bionic Pancreas makes 288 dosing decisions per day, 7 days per week, 365 days per year.
- The two Tandem t:slim pumps, one filled with insulin and the other with glucagon, receive dosing instructions from the iPhone every 5 minutes via Bluetooth. The doses of these two hormones are used to regulate blood glucose.
A glucose sensor is inserted into the body using an automated injector. A transmitter is then attached to enable transmission of glucose data wirelessly to the Dexcom receiver.
The iPhone is connected by cable to the Dexcom G4 receiver and runs a custom app that acts upon the glucose data by computing how much insulin or glucagon to deliver every 5 minutes. The app then sends these dosing instructions via Bluetooth to two pumps.
The pumps deliver the insulin and glucagon doses subcutaneously through separate infusion sets.