Current Research

National Science Foundation Engineering Research Center for Cellular Metamaterials  – T Bifano, Thrust Leader, Optical Engineering. CELL-MET aims to transform cardiovascular care by developing engineered cardiac tissue  patches, while also developing areas of expertise in education, diversity, administration, and outreach. Bifano leads the optics and photonics area of this project, focusing on optogenetics, volumetric microscopy, and mechanical stimulation of micro-tissue. 

National Science Foundation Research Traineeship (NRT) Program: Neurophotonics – T Bifano, PI: This is an interdisciplinary doctoral training program focused on neurophotonics, the use of light based tools to understand and control brain function. Our NRT community includes doctoral students in biology, neuroscience, biophysics, biomedical, and mechanical engineering.

Office of Naval Research Optical and Thermomechanical Design of High Reflectivity Deformable Mirrors (DMs), T Bifano PI, BU Subcontract, Funded through the JTO High Energy Laser Multidisciplinary Research Initiative (HEL-MRI) Program, J Talghader, University of Minnesota, PI. DMs use much of their available stroke to correct stress-induced mirror deformation. In this project, we are developing theory and techniques to minimize the effects of thermal deformation in DMs.

 National Science Foundation Major Research Instrumentation (MRI) Award: Development of a Holographic Nanoscale Optics Instrument – T Bifano, PI: Boston University researchers developed a shared facility comprised of a holographic near-field scanning atomic force microscope, combining near-field spectroscopies of elastic scattering, Raman and fluorescence over a wide wavelength range. The instrument allows phase-resolved near-field imaging to map 3D field response, and is currently operational as a shared facility in the laboratory of Bjoern Reinhard.

National Science Foundation Industry/University Cooperative Research Center for Biophotonics Sensors and Systems (CBSS) – T Bifano, PI: Boston University and the University of California at Davis established CBSS as a national resource for Biophotonic Sensors and Systems where photonics provides the enabling technologies for advances in methods to detect, sense, identify and understand biological properties, conditions or changes at the molecular and cellular/sub-cellular level.   Our recently completed Phase II effort focused on disease diagnosis, drug efficacy testing, patient drug effectiveness monitoring, and food & water safety.