Author: Thomas G Bifano

Axial localization in EDOF microscopy

New paper led by students Will Shain (now at Draper) and Nic Vickers, improving on EDOF microscopy technique by adding axial location. Applications in bacterial tracking and neural imaging are described.

New NSF Engineering Research Center: Engineered 3D Heart Tissue

Boston University has won an award from the National Science Foundation(NSF) to create a multi-institution Engineering Research Center (ERC), with the goal of synthesizing personalized heart tissue for clinical use.  The Bifano Lab will will direct imaging and optical engineering thrusts in this project.

Extended depth-of-field microscopy with a high-speed deformable mirror

Paper in Optics Letters: We present a wide-field fluorescence microscopy add-on that provides a fast, light-efficient extended depth-of-field (EDOF) using a deformable mirror with an update rate of 20 kHz. Out-of-focus contributions in the raw EDOF images are suppressed with a deconvolution algorithm derived directly from the microscope 3D optical transfer function. Demonstrations of the benefits […]

Summer design project: Keep EpiPens cool

EpiPens need to be kept within narrow temperature limits. They cannot be refrigerated, nor are they allowed to exceed 86°F. This summer we developed a low-cost, do-it-yourself solution for keeping EpiPens cool on summer outings. A short YouTube video highlights the results.

Will Shain presents two papers at OSA COSI Conference

Matched-Filter Compressive Imaging using a Deformable Mirror for Label-Free Flow Cytometry William Shain, Bennett Goldberg, Thomas Bifano, and Jerome Mertz Abstract: We distinguish geometric cell structures using a deformable mirror for high-throughput, label-free flow cytometry, overcoming approaches that can result in undesirable chemical modifications or low throughput. Extended abstract Novel Deconvolution Kernel for Extended Depth-of-Field […]